Equis ISSN 2398-2977

Ticarcillin

Contributor(s): Sally Anne Argyle

Introduction

Name

  • Ticarcillin.

Class of drug

  • Carboxypenicillin antibiotic.

Description

Storage requirements

  • After reconstitution it is stable for 48-72 h.

Uses

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Indications

  • Intrauterine treatment of endometritis caused by beta-hemolytic steptococci.
  • Principally indicated for the treatment of serious (usually but not exclusively life threatening) Pseudomonas aeruginosa Pseudomonas spp infections.
  • For pseudomonas septicemias ticarillin should be given with an aminoglycoside, eg gentamicin Gentamicin.
  • Activity against certain other gram-negative bacilli including Proteus spp Proteus spp and Bacteroides fragilis Bacteroides fragilis.

Administration

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Precautions

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Interactions

with other drugs

  • Often used with an aminoglycoside bacause of the synergistic effect seen with this combination.
  • Prior to administration do not mix ticarcillin with the aminoglycoside, since despite their synergyin vivothey will mutually inactivate each other in the syringe.

Further Reading

Publications

Other sources of information

  • Derived fromThe Veterinary Formulary.5th edn (2001) Ed: Bishop Y. Pharmaceutical Press; published is association with the British Veterinary Association, UK.
  • Prescott, Baggot & Walker (2000) EdsAntimicrobial Therapy in Veterinary Medicine.3rd edn. Ames, Iowa, Iowa State University Press, USA.

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