Equis ISSN 2398-2977

Ticarcillin

Contributor(s): Sally Anne Argyle

Introduction

Name

  • Ticarcillin.

Class of drug

  • Carboxypenicillin antibiotic.

Description

Storage requirements

  • After reconstitution it is stable for 48-72 h.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

  • Intrauterine treatment of endometritis caused by beta-hemolytic steptococci.
  • Principally indicated for the treatment of serious (usually but not exclusively life threatening) Pseudomonas aeruginosa Pseudomonas spp infections.
  • For pseudomonas septicemias ticarillin should be given with an aminoglycoside, eg gentamicin Gentamicin.
  • Activity against certain other gram-negative bacilli including Proteus spp Proteus spp and Bacteroides fragilis Bacteroides fragilis.

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

with other drugs

  • Often used with an aminoglycoside bacause of the synergistic effect seen with this combination.
  • Prior to administration do not mix ticarcillin with the aminoglycoside, since despite their synergyin vivothey will mutually inactivate each other in the syringe.

Further Reading

Publications

Refereed papers

Other sources of information

  • Derived from The Veterinary Formulary (2001) 5th edn. Ed: Bishop Y. Pharmaceutical Press; published is association with the British Veterinary Association, UK.
  • Prescott, Baggot & Walker (2000) Eds. Antimicrobial Therapy in Veterinary Medicine. 3rd edn. Iowa State University Press, USA.

ADDED