ISSN 2398-2977      

Ticarcillin

pequis
Contributor(s):

Sally Anne Argyle


Introduction

Name

  • Ticarcillin.

Class of drug

  • Carboxypenicillin antibiotic.

Description

Storage requirements

  • After reconstitution it is stable for 48-72 h.

Uses

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Indications

  • Intrauterine treatment of endometritis caused by beta-hemolytic steptococci.
  • Principally indicated for the treatment of serious (usually but not exclusively life threatening) Pseudomonas aeruginosa Pseudomonas spp infections.
  • For pseudomonas septicemias ticarillin should be given with an aminoglycoside, eg gentamicin Gentamicin.
  • Activity against certain other gram-negative bacilli including Proteus spp Proteus spp and Bacteroides fragilis Bacteroides fragilis.

Administration

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Precautions

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Interactions

with other drugs

  • Often used with an aminoglycoside bacause of the synergistic effect seen with this combination.
  • Prior to administration do not mix ticarcillin with the aminoglycoside, since despite their synergyin vivothey will mutually inactivate each other in the syringe.

Publications

Refereed papers

Other sources of information

  • Derived from The Veterinary Formulary (2001) 5th edn. Ed: Bishop Y. Pharmaceutical Press; published is association with the British Veterinary Association, UK.
  • Prescott, Baggot & Walker (2000) Eds. Antimicrobial Therapy in Veterinary Medicine. 3rd edn. Iowa State University Press, USA.
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