Equis ISSN 2398-2977

Sulfadoxine with Trimethoprim

Introduction

Name

  • Sulfadoxine with trimethoprim.

Class of drug

  • A potentiated sulfonamide: a sulfonamide (sulfadoxine) combined with a diaminopyrimidine (trimethoprim).

Uses

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Indications

  • Sulfadoxine/trimethoprim-sensitive infections.

Administration

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Precautions

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Interactions

with other drugs

  • Increased risk of cardiac arrhythmias when used alongside:
    • Detomidine.
    • Halothane.
    • Romifidine.
    • Xylazine.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Van Duijkeren E, Vulto A G & Van Miert A S (1994)Trimethoprim/sulfonamide combinations in the horse - a review.J Vet Pharmacol Ther17(1), 64-73.

Other sources of information

  • Derived fromThe Veterinary Formulary5th edn (2001) Bishop Y (Ed). British Veterinary Association and Royal Pharmaceutical Society.

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