Equis ISSN 2398-2977

Sodium thiosulfate

Synonym(s): Sodium thiosulphate Sodium hyposulfite

Introduction

Name

  • Sodium thiosulfate.

Class of drug

  • Antidote for cyanide (with sodium nitrite) poisoning in dogs and cats.
  • Antifungal.

Description

Chemical name

  • Sodium thiosulfite.

Molecular formula

  • Na2O3S2.

Molecular weight

  • 158.11.

Physical properties

  • Powder.
  • Water soluble.
  • Insoluble in alcohol.

Uses

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Indications

  • Cyanide poisoning.
  • Fungal skin infections, eg dermatophytosis.

Administration

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Beasley D M, Glass W I (1998) Cyanide poisoning - pathophysiology and treatment recommendations. Occup Med (Lond) 48 (7), 427-231.
  • Bhattacharya R (1995) Therapeutic efficacy of sodium nitrite and 4-dimethylaminophenol or hydroxylamine co-administration against cyanide poisoning in rats. Hum Exp Toxicol 14 (1), 29-33.
  • Koller W, Rotter M L & Gottardi W (1995) Do 'chlorine covers' exert a sustained bactericidal effect on the bacterial hand flora? J Hosp Infect 31 (3), 169-176.

Other sources of information

  • Tennant B (1999) Small Animal Formulary. 3rd edn. British Small Animal Veterinary Association. ISBN 0 905214 52 8.
  • Bishop Y (1998) The Veterinary Formulary. 4th edn. British Veterinary Association and Royal Pharmaceutical Society of Great Britain. ISBN 0853694 125.

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