Equis ISSN 2398-2977

Rifampicin

Contributor(s): Sally Anne Argyle

Introduction

Name

  • Rifampicin.

Class of drug

  • Rifamycin family of antimicrobials.

Uses

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Indications

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

  • Induction of microsomal enzymes decreases the half-life of the drug itself and may interfere with the half-life of other concurrently administered drugs such as corticosteroids, itraconazole, ketoconazole, warfarin and barbiturates.
  • Synergistic interaction with certain other antimicrobials, including erythromycin   Therapeutics: macrolides lincosamides   and penicillin G   Penicillin G  is observed and reduces the development of resistance.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references fromPubMedpublished during the last 12 months.

Other sources of information

  • Bertone J & Horspool L (2004) EdsEquine Clinical Pharmacology. Saunders. ISBN: 0702024848.
  • Derived fromThe Veterinary Formulary. (2004) 6th edn. Ed: Bishop Y. British Veterinary Association and Royal Pharmaceutical Society. ISBN: 0853695792.
  • Derived fromAntimicrobial Therapy(2000) 3rd edn. Eds: Prescott J F, Baggot J D & Walker R D. Iowa state University Press.

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