Equis ISSN 2398-2977

Phytomenadione

Synonym(s): Vitamin K

Introduction

Name

  • Phytomenadione.

Class of drug

  • Vitamin.
  • Pesticide antidote.

Uses

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Indications

  • Hypoprothrombinemia secondary to ingestion of anticoagulant rodenticides, eg warfarin , coumarin.
  • Management of Vitamin K1 deficiency in patients with fat malabsorption.
  • Treatment of Vitamin K1-dependent clotting factor abnormalities.

Administration

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Precautions

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Interactions

with other drugs

Mineral oil
  • Oral absorption of vitamin K is reduced by mineral oil   Liquid paraffin  .

with diagnostic tests

  • One stage prothrombin times (OSPT) to monitor therapy.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Derived from The Veterinary Formulary (1998) 4th edn. Ed: Bishop Y. British Veterinary Association and Royal Pharmaceutical Society.
  • Derived from The Small Animal Formulary (1999) 3rd edn. Ed: Tennant B. British Small Animal Veterinary Association.

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