Equis ISSN 2398-2977

Pethidine

Synonym(s): Meperidine hydrochloride, Pethidine hydrochloride (HCL

Contributor(s): Mark Senior

Introduction

Name

  • Pethidine hydrochloride.

Class of drug

  • Synthetic opioid analgesic.

Description

Chemical name

  • 1-methyl-4-phenyl-4-piperidinecarboxylic acid ethyl ester.
  • 1-methyl-4-phenylisonipecotic acid ethyl ester.

Molecular formula

  • C15H21NO2.

Physical properties

  • Tablets.
  • Solution.

Uses

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Indications

  • Moderate to severe pain, in particular equine colic.
  • Sedation.

Administration

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Precautions

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Interactions

with other drugs

  • Metoclopramide - antagonism as interacting drugs have opposing effects on gastrointestinal motility.
  • Combination with any other CNS depressant drug - enhanced depressant effects.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Derived from The Veterinary Formulary (1998) 4th edn. Ed: Bishop Y. British Veterinary Association and Royal Pharmaceutical Society.

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