Equis ISSN 2398-2977

Moxidectin

Introduction

Name

  • Moxidectin.

Class of drug

  • Macrocyclic lactone.
  • Semi-synthetic milbemycin.

Uses

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Indications

Endectocide
  • Moxidectin is an endectocide with activity against nematode and arthropod parasites.
  • The spectrum of activity is determined to some extent by the method of delivery.

Endoparasities

  • Efficacy against adult and larval stages of many helminth parasites of horses.
  • Active against:
    No action against trematodes, cestodes or protozoa.

Administration

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Pharmacokinetics

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Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Schumacher J, Livesey L, DeGraves F et al (2009) Efficacy of moxidectin against cyathostomins after long-term use in a large herd of draught horses with a high stocking density. Vet Rec 164 (21), 652-654 PubMed.
  • Schumacher J & Taintor J (2008) A review of the use of moxidectin in horses. Equine Vet Educ 20 (10), 546-551.
  • Bairden K, Davies H S, Gibson N R, Hood A J O & Parker L D (2006) Efficacy of moxidectin 2 per cent oral gel against cyathostomins, particularly third-stage inhibited larvae, in horses. Vet Rec 158 (22), 766-768 PubMed.
  • Holm-Martin M, Levot G W & Dawson K L (2005) Control of endoparasites in horses with a gel containing moxidectin and praziquantel. Vet Rec 156 (26), 835-838.
  • Hutchens D E & Paul A J (2000) Moxidectin; spectrum of activity and uses in an equine anthelmintic program. Comp Cont Educ Pract Vet 22 (4), 373-377.
  • Bauer C, Cirak V Y, Hermosilla C and Okoro H (1998) Efficacy of a 2 percent moxidectin gel against gastrointestinal parasites of ponies. Vet Rec 143, 558-561 PubMed.
  • Coles G C, Hillyer M H, Taylor F G R and Parker L D (1998) Activity of moxidectin against bots and lungworm in equids. Vet Rec 143, 169-170 PubMed.
  • Scholl P J (1998) Moxidectin 2% equine oral gel. Equine Pract 20, 19-22.
  • Blagburn B L and Lindsay D S (1998) Advances in parasitology. Comp Cont Ed Pract Vet 20, 415-416.

Other sources of information

  • Derived from The Veterinary Formulary (1998) 4th edn. Ed: Bishop Y. British Veterinary Association and Royal Pharmaceutical Society.

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