Equis ISSN 2398-2977

Morphine

Contributor(s): Mark Senior

Introduction

Name

  • Morphine.

Class of drug

  • Opioid analgesic.

Description

Chemical name

  • (5-alpha,6-alpha)-7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol.

Molecular formula

  • C17H19NO3.

Physical properties

  • Tablets.
  • Solution.

Uses

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Indications

  • Severe pain.

Administration

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Pharmacokinetics

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Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Villalba M, Santiago I & Gomex de Segura I A (2011) Effects of constant rate infusion of lidocaine and ketamine, with or without morphine, on isoflurane MAC in horses. Equine Vet J 43 (6), 721-726 PubMed.
  • Benredouane K, Ringer S K, Fourel I et al (2011) Comparison of xylazine-butrophanol and xylazine-morphine-ketamine infusions in horses undergoing a standing surgery. Vet Rec 169 (14), 364 PubMed.
  • Kalchofner K S, Kummer M, Price J & Bettschart-Wolfensberger R (2007) Pruritus in two horses following epidurally administered morphine. Equine Vet Educ 19 (11), 590-594.
  • Kamerling S, Wood T, DeQuick D, Weckman T J, Tai C, Blake J W & Tobin T (1989) Narcotic analgesics, their detection and pain measurement in the horse - a review. Equine Vet J 21 (1), 4-12 PubMed.
  • Combie J D, Nugent T E & Tobin T (1983) Pharmacokinetics and protein binding of morphine in horses. Am J Vet Res 44 (5), 870-874 PubMed.

Other sources of information

  • Derived from The Veterinary Formulary (1998) 4th edn. Ed: Bishop Y. British Veterinary Association and Royal Pharmaceutical Society.

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