Equis ISSN 2398-2977

Erythromycin

Contributor(s): Sally Anne Argyle

Introduction

Name

  • Erythromycin.

Class of drug

Uses

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Indications

  • Erythromycin-sensitive infections:
    • EspeciallyCampylobacterspp   Campylobacter spp  - drug of choice.
    • Streptococci.
    • Staphylococcus aureus  Staphylococcus aureus  - including penicillin-resistant strains.
    • Gram-negative bacteria.
    • Anaerobes.
    • Rhodococcus equi  Rhodococcus equi  in foals - drug of choice.
    • Bacterial eye infections.
    • Clinical and subclinical mastitis in cattle.
  • Less active againstMycoplasmaspp   Mycoplasmas and ureaplasmas  andSerpulina hyodysenterie.

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

Digoxin
  • May enhance absorption of digoxin   Digoxin  from the GI Tract.

Methylprednisolone

Theophylline

  • May increase serum levels of theophylline.

Terfenadine

  • May increase serum levels of terfenadine - in humans lead to fatal arrhythmias.

Warfarin

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references fromPubMedpublished during the last 12 months.
  • Stratton-Phelps M, Wilson W D & Gardner I A (2000)Risk of adverse effects in pneumonic foals treated with erythromycin versus other antibiotics - 143 cases (1986-1996).JAVMA217, 68-73PubMed.

Other sources of information

  • Bertone J & Horspool L (2004) EdsEquine Clinical Pharmacology. Saunders. ISBN: 0702024848.
  • Derived fromThe Veterinary Formulary. (2004) 6th edn. Ed: Bishop Y. British Veterinary Association and Royal Pharmaceutical Society. ISBN: 0853695792.
  • Derived fromAntimicrobial Therapy. (2000) 3rd edn. Eds: Prescott J F, Baggot J D, Walker R D. Iowa State University Press.

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