Equis ISSN 2398-2977

Ephedrine

Contributor(s): Adam Auckburally, Joanne Michou

Introduction

Name

  • Ephedrine.

Class of drug

  • Mixed alpha- and beta-adrenergic agonist.
  • Sympathomimetic amine.

Description

Chemical name

  • (R*,S*)-2-(methylamino)-1-phenylpropan-1-ol.

Molecular formula

  • C10H15NO.

Molecular weight

  • 165.23 g.

Physical properties

  • Colorless aqueous solution.

Storage requirements

  • <25°C.
  • Protect from light.

Uses

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Indications

The administration of ephedrine is not a substitute for appropriate fluid resuscitation during shock.

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

  • Monoamine oxidase inhibitors.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references fromPubMed.
  • Lee Y L, Clarke K W, Alibhai H I K & Song D Y (2002)The effects of ephedrine on intramuscular blood flow and other cardiopulmonary parameters in halothane-anesthetized ponies.VAA29(4), 171-181.

Other sources of information

  • Peck T E, Hill S A & Williams M (2005)Sympathomimetics. In:Pharmacology for Anaesthesia and Intensive Care. Greenwich Medical Media, London, UK. pp 187-208.

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