Equis ISSN 2398-2977

Dopamine hydrochloride

Contributor(s): Adam Auckburally, Eleanor Holden

Introduction

Name

  • Dopamine hydrochloride.

Class of drug

  • Catecholamine.
  • Sympathomimetic.
  • Adrenoceptor agonist.

Description

Chemical name

  • 4-(2-aminoethyl)benzene-1,2-diol.

Molecular formula

  • C8 H11 NO2 "HCl.

Molecular weight

  • 189.64 g.

Physical properties

  • Clear, odorless, aqueous solution.
  • Presented as a 40 mg/ml solution.

Storage requirements

  • Store at room temperature.
  • Protect from light.
  • Do not use if solutions become discolored as this indicates decomposition of the drug.
  • Infusions should be discarded after 24 h.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Pharmacokinetics

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

with other drugs

  • May reverse the effects of beta-blocking agents.

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Lee Y H et al (1998) Effects of dopamine, dobutamine, dopexamine, phenylephrine, and saline solution on intramuscular blood flow and other cardiopulmonary variables in halothane-anaesthetized ponies. Am J of Vet Res 59 (11), 1463-1472 PubMed.
  • Robertson S A et al (1996) Metabolic, hormonal, and hemodynamic changes during dopamine infusions in halothane anesthetized horses. Vet Surg 25 (1), 88-97 PubMed.
  • Trim C M et al (1991) Effects of an infusion of dopamine on the cardiopulmonary effects of Escherichia coli endotoxin in anaesthetised horses. Res Vet Sci 50 (1), 54-63 PubMed.
  • Trim C M et al (1989) Renal effects of dopamine infusion in conscious horses. Equine Vet J Suppl 17 (7), 124-128 PubMed.
  • Divers T J et al (1987) Acute renal failure in six horses resulting from haemodynamic causes.Equine Vet J 19 (13), 178-184 PubMed.
  • Trim C M et al (1985) Cardiopulmonary effects of dopamine hydrochloride in anaesthetised horses. Equine Vet J 17 (1), 41-44 PubMed.

ADDED