Equis ISSN 2398-2977

Dopamine hydrochloride

Contributor(s): Adam Auckburally, Eleanor Holden

Introduction

Name

  • Dopamine hydrochloride.

Class of drug

  • Catecholamine.
  • Sympathomimetic.
  • Adrenoceptor agonist.

Description

Chemical name

  • 4-(2-aminoethyl)benzene-1,2-diol.

Molecular formula

  • C8 H11 NO2 "HCl.

Molecular weight

  • 189.64 g.

Physical properties

  • Clear, odorless, aqueous solution.
  • Presented as a 40 mg/ml solution.

Storage requirements

  • Store at room temperature.
  • Protect from light.
  • Do not use if solutions become discolored as this indicates decomposition of the drug.
  • Infusions should be discarded after 24 h.

Uses

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Indications

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

  • May reverse the effects of beta-blocking agents.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references fromPubMed.
  • Lee Y Het al(1998)Effects of dopamine, dobutamine, dopexamine, phenylephrine, and saline solution on intramuscular blood flow and other cardiopulmonary variables in halothane-anaesthetized ponies.Am J of Vet Res59(11), 1463-1472PubMed.
  • Robertson S Aet al(1996)Metabolic, hormonal, and hemodynamic changes during dopamine infusions in halothane anesthetized horses.Vet Surg25(1), 88-97PubMed.
  • Trim C Met al(1991)Effects of an infusion of dopamine on the cardiopulmonary effects ofEscherichia coliendotoxin in anaesthetised horses.Res Vet Sci50(1), 54-63PubMed.
  • Trim C Met al(1989)Renal effects of dopamine infusion in conscious horses.Equine Vet J Suppl17(7), 124-128PubMed.
  • Divers T Jet al(1987)Acute renal failure in six horses resulting from haemodynamic causes.Equine Vet J19(13), 178-184PubMed.
  • Trim C Met al(1985)Cardiopulmonary effects of dopamine hydrochloride in anaesthetised horses.Equine Vet J17(1), 41-44PubMed.

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