Equis ISSN 2398-2977

Dobutamine

Contributor(s): Mark Senior

Introduction

Name

  • Dobutamine.

Class of drug

  • Adreno-receptor stimulant.

Description

Chemical name

  • (+/-)-4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]-1,2-benzenediol.
  • (+/-)-4-[2-[[3-(p-hydroxyphenyl)-1-methylpropyl]amino]ethyl]pyrocatechol.

Molecular formula

  • C18H23NO3.

Uses

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Indications

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

  • Beta-adrenoceptor blocking drugs - enhanced hypertensive effect, especially with non-selective beta-adrenoceptor blocking drugs.

Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Lee Y H, Clarke K W, Alibhai H I & Song D (1998)Effects of dopamine, dobutamine, dopexamine, phenylephrine and saline solution on intramuscular blood flow and other cardiopulmonary variables in halothane-anesthetized ponies.Am J Vet Res59(11), 1463-1472PubMed.
  • Raisis A L, Young L E, Blissitt K J, Walsh K, Meire H B, Taylor P M & Lekeux P (2000)Effect of a 30-minute infusion of dobutamine hydrochloride on hindlimb blood flow and hemodynamics in halothane-anesthetized horses.Am J Vet Res61(10), 1282-1288PubMed.

Other sources of information

  • Derived fromThe Veterinary Formulary.4th edn (1998) Bishop Y (Ed). British Veterinary Association and Royal Pharmaceutical Society.

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