Equis ISSN 2398-2977

Chlorhexidine

Contributor(s): Prof Derek Knottenbelt

Introduction

Name

  • Chlorhexidine.

Class of drug

  • Antiseptic.
  • Synthetic cationic compound.

Description

Chemical name

  • Chlorhexidine gluconate.

Molecular formula

  • C22H30Cl2N10.

Molecular weight

  • 505.45.

Uses

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Indications

  • Minor skin wounds.
  • Bacterial dermatitis. 
  • Skin disinfection and cleaning.
  • Surgical scrub.
  • Navel disinfection in neonatal foals - significantly better effect than even strong (7.5%) iodine solutions because of the duration of effect.

Administration

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Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Paterson S (1997) Dermatophytosis in 25 horses - a protocol of treatment using topical therapy. Equine Vet Educ 9, 171-172.
  • Southwood L L & Baxter G M (1996) Instrument sterilization, skin preparation, and wound management. Vet Clin North Am Equine Pract 12 (2), 173-194.
  • Dwyer R M (1995) Disinfecting equine facilities. Rev Sci Tech 14 (2), 403-418.
  • Russel A D (1986) Chlorhexidine: antibacterial action and bacterial resistance. Infection 14, 212-215.

Other sources of information

  • Derived from The Veterinary Formulary (1998) 4th edn. Ed: Bishop Y. British Veterinary Association and Royal Pharmaceutical Society.

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