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Calcium salts

pequis
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Synonym(s): Calcium gluconate, calcium borogluconate


Introduction

Name

  • Calcium salts.

Class of drug

  • Mineral.

Description

Chemical name

  • Calcium gluconate: D-gluconic acid calcium salt (2:1).
  • Calcium borogluconate: D-gluconic acid cyclic 4,5-ester + boric acid calcium salt (2:1).

Molecular formula

  • Calcium gluconate: C12H22CaO14.
  • Calcium borogluconate: C12H20B2CaO16.

Physical properties

  • Calcium gluconate: powder/tablets and solution.
  • 1 mg calcium = 11.2 mg calcium gluconate = 13.2 mg calcium borogluconate.
  • Calcium borogluconate: colorless or pale yellow sterile solution.

Storage requirements

  • Calcium borogluconate: <25°C.
  • Calcium borogluconate: protect from light.

Uses

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Indications

  • Prevention and treatment of hypocalcemia   Hypocalcemia  :
    • Mild hypocalcemia has been reported in horses with abdominal crises and may contribute to post-operative ileus and weakness.
    • In mares, lactation tetany can occur especially following stress   →   excitement, profuse sweating, stiffness and inco-ordination, which may lead to tetanic seizures.
    • Synchronous diaphragmatic flutter is most commonly found in exhausted and dehydrated horses. Hypocalcemia may contribute to increased phrenic nerve irritability.

Administration

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Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Derived from The Veterinary Formulary (1998) 4th edn. Ed: Bishop Y. British Veterinary Association and Royal Pharmaceutical Society.
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