Equis ISSN 2398-2977

Acepromazine

Synonym(s): Acetylpromazine, Acepromazine maleate, ACP

Contributor(s): Sally Anne Argyle, Mark Senior, Vetstream Ltd

Introduction

Name

  • Acepromazine.

Class of drug

  • Phenothiazine sedative.

Description

Chemical name

  • 1-[10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-yl]ethanone.
  • 10-[3-(dimethylamino)propyl]phenothiazin-2-yl methyl ketone.

Molecular formula

  • C19H22N2OS.C4H4O4.

Physical properties

  • Pale yellow injectable solution, gel or tablets.

Tablets are not licensed for use in horses in the UK.

Storage requirements

  • <25°C.

Uses

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Indications

  • Pre-anesthetic medication.
  • Sedation.

Administration

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Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Driessen B, Zarucco L, Kalir B & Bertolotti L (2011) Contemporary use of acepromazine in the anaesthetic management of male horses and ponies: A retrospective study and opinion poll. Equine Vet J 43 (1), 88-98 PubMed
  • Menzies-Gow N J (2008) Effects of sedation with acepromazine on echocardiographic measurements in eight healthy thoroughbred horses.Vet Rec 163 (1), 21-25 PubMed.

Other sources of information

  • Derived from The Veterinary Formulary (2001) 5th edn. Ed: Bishop Y. British Veterinary Association and Royal Pharmaceutical Society.

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