Equis ISSN 2398-2977

Uveitis: anterior - neoplasia-induced

Contributor(s): Dennis E Brooks, Graham Munroe, Rachel Murray, Anna Hollis

Overview

  • Intra-ocular neoplasia Eye: neoplasia - melanoma has been linked to the occurrence of anterior uveitis through alteration of normal immune function and direct tissue invasion.
  • Signs: depends on severity of inflammation, area(s) of uvea involved, duration of the problem. See also Uveitis: anterior - overview.
  • Diagnosis: full physical and ophthalmic examination, ultrasonography. See also Uveitis: anterior - overview.
  • Treatment: treat primary cause of uveitis. Cycloplegics, topical corticosteroids, systemic NSAIDs. See also Uveitis: anterior - overview.
  • Prognosis: dependent upon nature of tumor.

Presenting signs

  • Ptosis.
  • Miotic pupil.
  • Aqueous flare.
  • Hypotony.
  • Corneal vascularization.
  • Iris color changes.
  • Epiphora.
  • Blepharospasm.
  • Other clinical signs may be present depending on the primary neoplastic lesion.

Acute presentation

  • Acutely painful eye.
  • Miosis.
  • Blepharospasm.
  • Epiphora.
  • Other clinical signs depending on the primary neoplastic lesion.

Geographic incidence

  • May be seen anywhere in the world.

Age predisposition

  • Dependent on primary neoplastic process.

Pathogenesis

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Diagnosis

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Treatment

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Sequelae

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Montgomery K W (2014) Equine ocular neoplasia: a review. Equine Vet Educ 26 (7), 372-380.


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