Equis ISSN 2398-2977

Photodynamic therapy

Synonym(s): PDT

Contributor(s): Vetstream Ltd, Anna Hollis

Introduction

  • Photodynamic therapy (PDT) describes a method of cancer therapy using interactions of a photosensitizing agent, light and oxygen.
  • PDT is a promising method of treating superficial squamous cell carcinomas (SCC) Skin: neoplasia - squamous cell carcinoma that is non-invasive, provides good cosmesis and carries minimal risk of toxicity.
  • It may also be a useful adjunctive treatment for small sarcoids Sarcoid, especially following surgical removal.
  • The photosensitizer is quite expensive, so for large areas, this may prove a financially prohibitive limitation.

Indications

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Principles

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History and background

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Veterinary clinical results

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Conclusion and future directions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Golding J P, Kemp-Symonds J G & Dobson J M (2017) Glycolysis inhibition improves photodynamic therapy response rates for equine sarcoids. Vet Comp Oncol 15 (4), 1543-1552 PubMed.
  • Buchholz J & Walt H (2013) Veterinary photodynamic therapy: a review. Photodiagnosis Photodynamic Therapy 10 (4), 342-347 PubMed.
  • Martens A, Moor A D E, Waelkens E, Merlevede W & De Witte P (2000) In vitro and in vivo evaluation of hypericin for photodynamic therapy of equine sarcoids. The Vet J 159 (1), 77-84 PubMed.


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