Equis ISSN 2398-2977

Muscle: biopsy

Contributor(s): Helen Herinckx, Catherine McGowan, Catherine McGowan

Introduction

  • Muscle biopsy is an under utilized technique that can provide valuable information about the etiology of neuromuscular conditions.
  • It would be primarily used in the investigation of recurrent or rhabdomyolysis   Muscle: myopathy - exertional rhabdomyolysis  and muscle wasting associated with neuromuscular disease, particularly suspected EMND   Neurology: motor neuron disease  .
  • While typically used for generalized muscle disorders, it is also useful for localized muscle disorders, eg myositis.

Indications

  • Recurrent rhabdomyolysis   Muscle: myopathy - exertional rhabdomyolysis  .
  • Shivering.
  • Hindlimb weakness.
  • Hindlimb muscle atrophy   Hindlimb: muscle atrophy 01    Hindlimb: muscle atrophy 02  .
  • Generalized weakness and atrophy.
  • Local muscle swelling, pain or atrophy of unknown etiology.

techniques for recurrent rhabdomyolysis

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

techniques for neuromuscular disorders: equine motor neuron disease

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

techniques for localized muscle disorders

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Sampling, handling and processing

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers
  • Recent references fromPubMedpublished during the last 12 months.
  • Stanley R L, Maile C & Piercy R J (2009)Storage-associated artefact in equine muscle biopsy sample. Equine Vet J41(1), 82-86.
  • Ledwith A & McGowan C M (2004)Muscle biopsy: a routine diagnostic procedure. Equine Vet Educ16(2), 62-67.
  • Valentine B A, Divers T J et al(1998)Muscle biopsy diagnosis of motor neuron disease and equine polysaccharide storage myopathy. Equine Vet Educ10, 42-50.


ADDED