ISSN 2398-2977      

Uveitis: recurrent

pequis
Contributor(s):

Joseph Bertone

Synonym(s): Periodic ophthalmia, Moon blindness, Iridocyclitis


Introduction

  • Cause: idiopathic uveitis is characterized by lack of evidence of obvious etiology.
  • Incidence: single or recurrent (more usual) episodes of clinical signs of a varying periodicity.
  • Signs: sudden onset unilateral or bilateral (more usual) acutely painful eye   →   progressive, irreversible ocular pathology with increasing numbers of flare-ups; a whole range of acute and chronic ocular changes varying with individual cases.
  • Treatment: rapid and intense topical and systemic therapy to minimize long-term sequalae.
  • Prognosis: guarded: see equine anterior uveitis: overview   Uveitis: anterior - overview  .
  • A common cause of blindness in horses.

Pathogenesis

Etiology

Pathophysiology

  • Idiopathic uveitis - characterized by the absence of historical or clinical evidence of an obvious etiology.
  • A single or recurrent (more usual) acute episode of uveitis with a varying periodicity.
  • Probably a group of immunologically mediated, etiologically and pathologically distinct conditions.
  • Recurring episodes of acute anterior uveitis and/or chorioretinitis/optic neuritis are associated with progressive, irreversible ocular pathology which is dependent upon the severity and duration of each exacerbation and the promptness/effectiveness of therapy.
  • See immune-mediated anterior uveitis   Uveitis: anterior - immune-mediated  .

Diagnosis

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Treatment

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Prevention

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Annear M J, Gemensky-Metzler A J & Wilkie D A (2012) Uveitic glaucoma in the horse. Equine Vet Educ 24 (2), 97-105 VetMedResource.
  • Matas M & Donaldson D (2010) Bilateral suprachoroidal ciclosporine implant in a horse with equine recurrent uveitis. UK Vet 15 (8), 4-8 VetMedResource.
  • Frellstedt L (2009) Equine recurrent uveitis: A clinical manifestation of leptospirosis. Equine Vet Educ 21 (10), 546-552 VetMedResource.
  • Deeg C A, Marti E, Gaillard C & Kaspers B (2004) Equine recurrent uveitis is strongly associated with the MHC class I haplotype ELA-A9. Equine Vet J 36 (1), 73-75 PubMed.
  • Nasisse M P & Nelms S (1992) Equine ulcerative keratitisVet Clin North Am Equine Pract (3), 537-555 PubMed.

Other sources of information

  • Brooks D E (2004) Surgical Management of Equine Recurrent Uveitis. In: Proc 43rd BEVA Congress. Equine Vet J Ltd, UK. pp 153.

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