Equis ISSN 2398-2977

Skin: fibroma / fibrosarcoma

Contributor(s): Rosanna Marsella, Anna Hollis

Introduction

  • Uncommon tumor of dermal or subcutaneous origin, however one of the most common neoplasms in the frog of the horse's foot.
  • 12.5% of fibrosarcomas were found in the skin in one report.
  • Cause: unknown.
  • Signs: nodules in dermis or subcutaneous tissue +/- ulceration.
  • Diagnosis: histopathology.
  • Treatment: surgical excision.
  • Prognosis: fibroma: good; fibrosarcoma: guarded.

Pathogenesis

Predisposing factors

General

  • Fibrosarcoma has been reported to arise in burn wounds of a horse.

Pathophysiology

  • Unknown.
  • Fibroma considered a benign lesion.
  • Fibrosarcoma are locally invasive, metastasis in 25% of cases.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Voute L C (2010) Fibro-osseous tumours in the horse: A reminder of the importance of a multidisciplinary approach to diagnosis. Equine Vet Educ 22 (1), 66 WileyOnline.
  • Pieber K, Kuebber-Heiss A, Kuebber P & Kofler J (2010) Fibro-osseous tumour of the fourth metacarpal bone in a horse: Clinical, radiographic and long-term post operative findings. Equine Vet Educ 22 (2), 62-65 VetMedResource.
  • Trostle S S et al (2005) Juvenile mandibular ossifying fibroma in a 12-week-old foal. Equine Vet Educ 17 (6), 284-286 VetMedResource.
  • Henson F M D & Dobson J M (2004) Use of radiation therapy in the treatment of equine neoplasia. Equine Vet Educ 16 (6), 315-318 VetMedResource.
  • Hikita M, Ishikawa Y, Shibahara T & Kadota K (2004) Mesenteric myofibroblastoma in a horse. Vet Rec 154 (25), 795-796 PubMed.
  • Roels S et al (1998) Successful treatment of an equine preputial fibrosarcoma using 5-fluorouracil/evaluation of the treatment using quantitative PCNA and Ki67 (MIB 1) immunostaining (Case report). Zentralbl Veterinarmed A 45 (10), 591-598 PubMed.
  • Schooley E K et al (1998) Musculoskeletal system neoplasia. Vet Clin North Am Equine Pract 14 (3), 535-542 (Review) PubMed.

Other sources of information

  • Knottenbelt D C, Patterson-Kane J C & Snalune K L (2015) Clinical Equine Oncology. Elsevier, UK.


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