Equis ISSN 2398-2977

Intestine: enteritis

Contributor(s): Prof Jonathon Naylor

Introduction

  • Eosinophilic gastroenteritis is a cause of chronic inflammatory bowel disease.
  • Cause: unknown.
  • Signs: weight loss, inappetance and edema.
  • Diagnosis: clinical signs, rectal findings, and gut biopsy.
  • Treatment: supportive therapy, eg fluids, intestinal adsorbants, probsotics etc.
  • Prognosis: poor if eosinophilic enteritis.

Pathogenesis

Etiology

  • Unknown.

Pathophysiology

  • Inciting cause (unknown)   →   mucosal inflammation, and the infiltration of the gut wall with eosinophilic cells.
  • Villous atropy and leakage of protein and electrolyte may follow   →   decreased reabsorption of water from the feces.
  • Skin lesions also occur, and often are the presenting problem.
  • Mucosal inflammation and infiltration   →   protein losing enteropathy and loss of fluid, as well as lack of reabsorption of water due to villous atrophy, another consequence of gut wall inflammation.
  • Reduced carbohydrate absorption, hypoalbuminemia, and hypoproteinemia commonly occur.
  • Diffuse eosinophilic infitration of the regional lymph nodes, and organs adjacent to the gut as well as extra-intestinal tissues such as the skin also occurs.
  • Skin lesions are a common feature.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Blunden A S, Smith K C, Neal H N & Dugdale D J (2006)Enteritis associated with infection by Campylobacter jejuni in two Thoroughbred foals.Equine Vet Educ18(1), 8-10 VetMedResource.
  • Swain J M, Licka T, Rhind S M & Hudson N P (2003)Multifocal eosinophilic enteritis associated with a small intestinal obstruction in a standardbred horse.Vet Rec24(152), 645-651 PubMed.
  • Lindberg Ret al(1996)Rectal biopsy diagnosis in horses with clinical signs of intestinal disorders, a retrospective study of 116 cases.Equine Vet J28(4), 275-284 PubMed.
  • Love S, Mair T S & Hillyer M H (1992)Chronic diarrhea in adult horses - a review of 51 referred cases.Vet Rec130(11), 217-219 PubMed.
  • Cohen N Det al(1992)Eosinophilic gastroenteritis with encapsulated nematodes in a horse.JAVMA200(10), 1518-1520 PubMed.
  • Pass D Aet al(1982)Chronic eosinophilic gastroenteritis in the horse.Vet Pathol19(5), 486-496 PubMed.

Other sources of information

  • Rose R J & Hodgson D R (1993)Manual of Equine Practice.Saunders. ISBN 0 7216 3739 6.


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