ISSN 2398-2977      

Equine adenovirus infection (EAI)

pequis

Introduction

Pathogenesis

Etiology

Predisposing factors

General
  • Failure of passive transfer.
  • Young immunologically naive animals.

Specific

Pathophysiology

  • EAV probably persists latently in pharyngeal lymphoid tissues and URT of apparently healthy animals for long periods, especially in adults.
  • Latency acts as source for inhalation infection of others, especially foals   →   an asymptomatic or mild URT disease.
  • In Arabian foals with SCID the virus is able to proliferate in and attack the respiratory epthelium (especially in lung)   →   cell death and epithelial hypoplasia.
  • Epithelial cells slough into alveolar/bronchiolar lumen   →   pulmonary atelectasis and bronchopneumonia.

Timecourse

  • Arabian foals: first few weeks of life.

Diagnosis

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Treatment

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Prevention

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Outcomes

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Bell S A, Leclere M, Gardner I A & Maclachlan (2006) Equine adenovirus 1 infection of hospitalised and healthy foals and horses. Equine Vet J 48 (4), 379-381 VetMedResource.
  • Acland H M et al (1983) Ulcerative duodenitis in foals. Vet Pathol 20 (6), 653-661 PubMed.
  • Campbell T M et al (1983) Attempted reconstitution of a foal with primary severe combined immunodeficiency. Equine Vet J 15 (3), 233-237 PubMed.
  • Perryman L E et al (1978) Maintenance of foals with combined immunodeficiency, causes and control of secondary infections. Am J Vet Res 39 (6), 1043-1047 PubMed.
  • Whitlock R H et al (1975) Adenoviral pneumonia in a foal. Cornell Vet 65 (3), 393-401 PubMed.
  • McChesney A E et al (1974) Experimental transmission of equine adenovirus in Arabian and non-Arabian foals. Am J Vet Res 35 (8), 1015-1023 VetMedResource.

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code