Equis ISSN 2398-2977

Endometrium: hypoplasia

Contributor(s): Terry Blanchard, Jean Pierre Held, Madeleine L H Campbell

Introduction

  • Cause: immaturity (most commonly), gonadal dysgenesis, ovarian neoplasia.
  • Signs: failure of conception.
  • Diagnosis; history, ultrasonography, endometrial biopsy and histopathology, chromosomal karyotyping.
  • Treatment: depends on cause. Time if immaturity, surgical removal of tumor if ovarian neoplasia, no treatment possible if gonadal dysgenesis.
  • Prognosis: depends on cause. Good for immaturity; guarded for ovarian neoplasia; hopeless for gonadal dysgenesis.

Pathogenesis

Pathophysiology

  • Diffuse endometrial glandular under-development or delayed development.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Snider T A, Sepoy C & Holyoak G R (2011) Equine endometrial biopsy reviewed: observation, interpretation and application oaf histopathologic data. Theriogenology 75 (9), 1567-1581 PubMed.
  • Schlafer D H (2007) Equine endometrial biopsy: enhancement of clinical value by more extensive histopathology and application of new diagnostic techniques? Theriogenology 68 (3), 413-422 PubMed.
  • Ricketts S W & Barrelet A (1997) A restrospective review of the histopathological features seen in a series of 4241 endometrial biopsy samples collected from UK Thoroughbred mares over a 25 year period. Pferdeheilkunde 13 (5), 525-530 PferdeheilkundeOnline (pdf download).
  • Kenney R M (1978) Cyclic and pathologic changes of the mare endometrium as detected by biopsy, with a note on early embryonic death. JAVMA 172 (3), 241-262 PubMed.

Other sources of information

  • Ricketts S W & Troedsson M H T (2007) Fertility Expectations and Management for Optimal Fertility. In: Current Therapy in Equine Reproduction. Eds: Samper J C, Pycock J F & McKinnon A O. Elsevier. pp 53-69.


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