Equis ISSN 2398-2977

Cerebellum: hypoplasia

Contributor(s): Caroline Hahn, Robert J MacKay, Graham Munroe

Introduction

  • Uncommon cause of seizures in neonatal foals.
  • Cause: congenital developmental abnormality.
  • Signs: seizures/convulsions; gait abnormalities.
  • Diagnosis: history and clinical signs; computed tomography.
  • Treatment: none.
  • Prognosis: hopeless in severe cases.

Pathogenesis

Etiology

  • Developmental abnormality.

Pathophysiology

  • Functions of the cerebellum:
    • Regulates rate, strength and range of movement.
    • Co-ordinates balance and posture.
  • Cerebellar abnormalities have a profound effect on gait and posture.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Cudd T A, Mayhew I G & Cottrill C M (1989) Agenesis of the corpus callosum with cerebellar vermian hypoplasia in a foal resembling the Dandy-Walker syndrome - pre-mortem diagnosis by clinical evaluation and CT scanning. Equine Vet J 21 (5), 378-381 PubMed.
  • Welchli R O & Ehrensperger F (1988) Two related cases of cerebellar abnormality in equine fetuses associated with hydrops of fetal membranes. Vet Rec 123 (20), 513-514 PubMed.

Other sources of information

  • Byrne B A (2004) Diseases of the Cerebellum. In: Equine Internal Medicine. 2nd edn. Eds: Reed S M, Bayly W M & Sellon D C. Saunders, USA. pp 588-594. ISBN: 0 7216 9777 1.


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