Equis ISSN 2398-2977

Pneumocystis carinii

Synonym(s): P. carinii

Contributor(s): Christopher Brown, Susan Dawson

Introduction

Classification

Taxonomy

  • Phylum: Sarcomastigofora.
  • Subphylum: Sarcodina.
  • GenusPneumocystis.
  • Speciescarinii.

Etymology

  • Greek: pneuma- wind, spirit, air; kustis- bladder.
  • Latin: carina- keel, ridge.

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Clinical Effects

Epidemiology

Habitat

  • Main habitat - mammalian respiratory tract.

Lifecycle

  • Direct lifecycle.
  • Evaluation of FNA sequences suggests thatP. cariniimay be more closely related to fungi than protozoa.
  • Multiplies in lungs when host becomes immunosuppressed.

Transmission

  • Usually from infected to susceptible animal within species.
  • Infected aerosol.

Pathological effects

  • Usually confined to lung.
  • Interstitial pneumonia associated with large numbers ofP. cariniiorganisms in alveolar spaces.

Other Host Effects

  • Most infections latent or subclinical.

Control

Control via chemotherapies

Diagnosis

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Perron Lepage M F et al (1999) A case of interstitial pneumonia associated with Pneumocystis carinii in a foal. Vet Pathol 36 (6), 621-624 PubMed.
  • Ewing P J et al (1994) Pneumocystis carinii pneumonia in foals. JAVMA 204 (6), 929-933 PubMed.
  • Tanaka S et al (1994) Pneumocystis carinii pneumonia in a Thoroughbred foal. J Clin Microbiol 32 (1), 213-216 PubMed.
  • Ainsworth D M, Weldon A D, Beck K A & Rowland P H (1993) Recognition of Pneumocystis carinii in foals with respiratory distress. Equine Vet J 25 (2), 103-108 PubMed.
  • Masur H (1992) Prevention and treatment of pneumocystis pneumonia. New England J Med 327, 1853.

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