Equis ISSN 2398-2977

Candida albicans

Synonym(s): C. albicans

Contributor(s): Susan Dawson, Richard Walker

Introduction

Classification

Taxonomy

  • GenusCandida.
  • Speciesalbicans.

Etymology

  • L:candidus, candere- to glisten.
  • L:albus- white.

Active Forms

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Clinical Effects

Epidemiology

Habitat

  • Mucous membranes, especially intestinal and genital tracts, of many species.

Transmission

  • Usually endogenous.

Pathological effects

  • Immunosuppression is an important predisposing factor to disease development due to this organism.
  • Main defense is neutrophil phagocytosis.
  • Neuraminidase and proteases may play a part in virulence.
  • Cell wall glycoproteins have an endotoxin-like activity.
  • Granulomas are rare; the inflammatory response is usually neutrophilic.
  • Lesions characterised by non-healing ulcers covered with white plaques.
    diseases caused
  • Genital tract infection: equine, human .
  • Stomatitis /enteric infection: avian, young equine, bovine, canine, swine, humans.
  • Respiratory tract/lung infection: young bovine, feline, human.
  • Mastitis: bovine (usually mild infection - may be introduced during administration of antibiotics).
  • Systemic infection: neonatal foals.

Other Host Effects

  • Common commensal on mucous membranes.

Control

Control via animal

  • Correct underlying clinical condition, eg immunosuppressive disease.

Control via chemotherapies

Topical

Vaccination

  • None available.

Diagnosis

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Reilly L K & Palmer J E (1994) Systemic candidiasis in 4 foals. JAVMA 205 (3), 464-466 PubMed.

Other sources of information

  • Biberstein E L (1990) Candida. In: Review of Veterinary Microbiology. Eds: E L Biberstein and Y C Zee. Blackwell Scientific, USA. pp.141-145. ISBN 0 86542 085 8.

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