ISSN 2398-2942      

Mexiletine

icanis
Contributor(s):

Vetstream Ltd


Introduction

Name

  • Mexiletine.

Class of drug

  • Class 1b antidysrhythmic agent.

Uses

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Indications

  • May be useful in dogs where lidocaine is ineffective.
  • Used in human medicine to control ventricular arrhythmias Heart: dysrhythmia following myocardial infarction.

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

Atropine and opioid analgesics

Acetazolamide and alkaline urine

  • Mexiletine excretion may be reduced (due to antacids and adsorbents) Acetazolamide.

Phenytoin and rifampicin

  • The metabolism of mexiletine may be increased Phenytoin.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • BSAVA Small Animal Formulary. Ramsey I (2017) 9th edn. BSAVA, UK.
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