ISSN 2398-2942      

Lactated Ringer's solution

icanis
Contributor(s):

Synonym(s): Hartmann's


Introduction

Name

  • Lactated Ringer's Solution (LRS).

Class of drug

  • Isotonic electrolyte solution.

Description

Molecular formula

  • Each litre contains:
    • 6.0 g sodium chloride.
    • 0.4 g potassium chloride.
    • 0.27 g calcium chloride dehydrate.
    • 28.9 ml of molar sodium lactate.

Physical properties

  • Clear colorless solution.

Storage requirements

  • Store at 2-25°C (shelf-life 2 years).
    Discard after single dose.

Uses

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Indications

  • LRS is an isotonic balanced electrolyte solution.
  • Its makeup is similar to extracellular fluid.
  • Water/electrolyte replacement.
  • LRS is a replacement solution. It is designed to be administered rapidly in large volumes. Its composition is such that it should not significantly disrupt plasma electrolyte concentrations.
  • LRS may be used as a maintenance fluid if potassium is added.
  • Metabolic acidosis.
  • Lactate is added to act as an alkalinizing agent.

Administration

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Pharmacokinetics

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Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Based on Tennant B (1999) Small Animal Formulary. 3rd edn. Cheltenham: BSAVA.
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