Canis ISSN: 2398-2942

L-carnitine

Synonym(s): Carnitine, levocarnitine, levocarnitinum

Contributor(s): Craig B Webb

Introduction

Name

  • L-carnitine.

Class of drug

  • Amino acid derivative.

Description

Chemical name

  • (R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium chloride.

Molecular formula

  • C7H16NO3.Cl

Molecular weight

  • 161.

Physical properties

  • Powder.

Storage requirements

  • Keep tightly closed, store at room temperature.

Uses

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Indications

  • Dilated cardiomyopathy Heart: dilated cardiomyopathy (DCM) in the dog (eg American Cocker spaniels, Boxers).
  • Hepatic lipidosis in the cat.
  • May provide protection against cardiomyopathy induced by doxorubicin Doxorubicin.
  • Potentially improves fat metabolism and excretion during weight loss in the dog.

Administration

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Pharmocokinetics

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Precautions

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Interactions

with other drugs

  • Potential for interaction with valproic acid:
    • L-carnitine doses may need to be increased.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Based on Plumb's Veterinary Drug Handbook. Plumb, Donald (2011)7th Edition.
  • Small Animal Drug Handbook.

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