ISSN 2398-2942      

Chlorothiazide

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Introduction

Name

  • Chlorothiazide.

Class of drug

  • Thiazide diuretic.

Description

Chemical name

  • 6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide.

Molecular formula

  • C7H6ClN3O4S2.

Physical properties

  • Colorless.

Uses

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Indications

Administration

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Precautions

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Interactions

with other drugs



Corticosteroids
  • Increased risk of hypokalemia.
Diazoxide
  • Concurrent administration may lead to hyperglycemia and hypotension.
Calcium salts or Vitamin D
  • Risk of hypercalcemia if thiazides are administered concurrently with calcium ot Vitamin D Vitamin D.
Sulfonamides
  • May potentiate thiazide activity.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Based on Small Animal Formulary. Tennant, Bryn (1999) 3rd edn. Cheltenham: BSAVA.
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