Canis ISSN: 2398-2942

Alfaxalone (Alfaxan)

Synonym(s): Alfaxan-CD RTU (where CD=cyclodextrin; RTU=ready to use)

Contributor(s): Len Cullen, Polly Taylor, Jo Murrell

Introduction

Name

  • Alfaxalone (Alfaxan).

Class of drug

  • Steroid general anesthetic.

Description

Chemical name

  • 3-hydroxy-5-pregnane-11, 20-dione.

Physical properties

  • Clear, colorless solution for injection presented in a multi-dose bottle.
  • pH of solution: 6.5 to 7.0.
  • Concentration: 10 mg/ml.

Storage requirements

  • Store below 30°C.
  • Protect from light.
  • Multi-dose vial with preservative now available - use within 28 days of broaching the vial.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

  • Injectable anesthetic agent for dogs and cats.
  • Given alone as a single bolus dose, in incremental doses or by continuous rare infusion (CRI).
  • Given for anesthetic induction prior to tracheal intubation Endotracheal intubation and maintenance with inhalational anesthesia Anesthesia: maintenance.
  • Give intramuscularly to induce a brief period of sedation (10-15 mins).

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed papers

Other sources of information

  • BSAVA Small Animal Formulary. Ramsey I (2017) 9th edn. 
  • Technical Manual, Jurox Pty Ltd, Rutherford. NSW 2320, Australia.

ADDED