Canis ISSN: 2398-2942

Acetazolamide

Contributor(s): Dennis E Brooks, Vetstream Ltd

Introduction

Name

  • Acetazolamide.

Class of drug

  • Carbonic anhydrase inhibitor.

Description

Chemical name

  • N-[5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide.
  • 5-acetamido-1,3,4-thiadiazole-2-sulfonamide.

Molecular formula

  • C4H6N4O3S2.

Uses

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Indications

No longer used for acute glaucoma Glaucoma.

Administration

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Precautions

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Interactions

with other drugs

  • Primidone Primidone absorption may be inhibited by oral acetazolamide.
  • Acetazolamide alkalinizes urine, thus the excretion rate of weak bases may be decreased, but weak acids increased.
  • With corticosteroids may increase potassium loss causing hypokalemia Hypokalemia.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Ramsey I (2017) BSAVA Small Animal Formulary. 9th edn. 

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