ISSN 2398-2942      

Fluid therapy: for acid-base imbalance

icanis

Acid-base imbalance

  • Generally, it is most important to correct the underlying cause that led to acid-base imbalance Acid base imbalance.
  • Normal kidneys will correct mild to moderate acid-base imbalance as long as adequate circulating blood volume is restored.

Acidosis

  • pH >7.1’ infusion of crystalloid solution, such as Hartmann's solution, will dilute the acidosis and improve renal perfusion.
  • pH <7.1’ bicarbonate infusion may be given. Total MEq NaHCO3 = 0.3 x bodyweight (kg) x base deficit. Give half of this amount slowly, then re-evaluate.
    For composition of solutions see the parenteral fluids comparison table Parenteral fluids comparison table.
  • If metabolic acidosis is strongly suspected from the clinical history and signs but blood-gas analysis is unavailable, then 1-2 MEq/kg bicarbonate Sodium bicarbonate - may be given slowly.
    Bicarbonate administration can be dangerous if unnecessary or too rapid. Side-effects include paradoxical cerebrospinal fluid (CSF) analysis, hypokalemia, overshoot alkalosis and reduced O2 supply to tissues.It is easier to correct acidosis than alkalosis.

Alkalosis

  • Metabolic acidosis may be corrected rapidly by ECF expansion with 0.9% NaCl.
  • Administration of chloride - encourages renal excretion of bicarbonate ion.
  • Concurrent hypokalemia is common and should be corrected by supplementing fluids with KCl.

Further Reading

Publications

Refereed papers

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code