ISSN 2398-2969      

Polycythemia: primary

icanis
Contributor(s):

Ruthanne Chun

Synonym(s): Erythroblastic leukemia, Polycythemia vera


Introduction

  • Includes erythroblastic leukemias (extremely rare) and polycythemia vera (rare).
  • Polycythemia without increased [erythropoietin].
  • Signs: brick red mucous membranes, polydipsia, polyuria and signs referable to hyperviscosity.
  • Diagnosis: eliminate causes of secondary polycythemia Polycythemia: secondary ; bone marrow aspiration.
  • Treatment: phlebotomy, cytotoxic agents.
  • Prognosis: reasonable.

Pathogenesis

Etiology

  • Unknown.

Pathophysiology

  • Increased production of red blood cells → blood hyperviscosity → cell aggregates in brain and lungs → neurological signs.

Timecourse

  • Weeks to months.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Comazzi S, Sacchet A, Milani F, Paltriniere A & Agnes F (2000) Some aspects of erythrocyte metabolism in a dog with polycythaemia vera. Vet Rec 147 (12), 331-334 PubMed.
  • Campbell K L (1990) Diagnosis and management of polycythemia in dogs. Comp Cont Ed Pract Vet 12 (4), 543-550 VetMedResource.
  • McGrath C J, Krawiec D R & Johnston S D (1982) Canine polycythemia vera, a review of diagnostic features. Vet Med 77 (4), 611-613 VetMedResource.

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