ISSN 2398-2969      

Pickwickian syndrome

icanis
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Introduction

  • Term borrowed from human medicine used to describe Mr Pickwick who suffered respiratory embarrassment due to obesity.
  • Cause: obesity.
  • Signs: respiratory distress.
  • Diagnosis: signs.
  • Treatment: weight loss.
  • Prognosis: good if adequate weight is lost.

Pathogenesis

Predisposing factors

General
  • Predisposers for obesity:
    • Inactivity.
    • Osteoarthritis → reduced exercise.
    • Medical causes, eg hypothyroidism Hypothyroidism.

Pathophysiology

  • Pickwickian syndrome is a term borrowed from human medicine.
  • Human patients have decreased alveolar ventilation but normal blood gas analysis.
  • Obesity → physiological changes such as decreased cardiac compliance and lung compliance.

Timecourse

  • Chronic insidious development over months.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

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