Canis ISSN: 2398-2942

Osteosarcoma: axial skeleton

Synonym(s): OSA, osteosarcoma

Contributor(s): Laura Garrett, Andy Moores

Introduction

  • Osteosarcoma of the axial skeleton behaves similarly to appendicular neoplasia, except for the mandible (less malignant).
  • Signs: firm, bony swelling, other signs are site specific eg dysphagia (oral OSA), nasal discharge (nasal OSA), neurological signs and pain (vertebral OSA).
  • Diagnosis: radiography, biopsy.
  • Treatment: radical surgical resection.
  • Prognosis: guarded, but may be better than for osteosarcoma of long bones Osteosarcoma. Prognosis for mandibular OSA may be slightly better. Much better prognosis associated with parosteal osteosarcoma (juxtacortical OSA).

Pathogenesis

Timecourse

  • Weeks to months.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Dickerson M E, Page R L et al (2001) Retrospective analysis of axial skeleton osteosarcoma in 22 large-breed dogs. J Vet Intern Med 15 (2), 120-124 PubMed.
  • Hammer A S, Weeren F R et al (1995) Prognostic factors in dogs with osteosarcomas of the flat or irregular bones. JAAHA 31 (4), 321-326 PubMed.
  • Pirkey-Ehrhart N, Withrow S J et al (1995) Primary rib tumors in 54 dogs. JAAHA 31 (1), 65-69 PubMed.
  • Heyman S J, Diefenderfer D L et al (1992) Canine axial skeletal osteosarcoma - a retrospective study of 116 cases (1986-1989). Vet Surg 21 (4), 304-310 PubMed.
  • Matthiesen D T, Clark G N et al (1992) En bloc resection of primary rib tumors in 40 dogs. Vet Surg 21 (3), 201-204 PubMed.
  • Withrow S J & Doige C E (1980) En bloc resection of a juxtacortical and three intra-osseous osteosarcomas of the zygomatic arch in dogs. JAAHA 16 (6), 867-872 VetMedResource.


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