Canis ISSN: 2398-2942

Enteritis: granulomatous

Synonym(s): Regional enteritis

Introduction

  • Very rare, idiopathic granulomatous inflammation causing (sometimes palpable) thickening of ileum, more common in colon.
  • Signs: chronic diarrhea, weight loss +/- abdominal pain, hematochezia/melena.
  • Diagnosis: imaging (radiography and ultrasound), endoscopy and biopsy.
  • Treatment: surgical resection of affected area followed by medical treatment.
  • Prognosis: guarded.

Pathogenesis

Etiology

  • Unknown, may be related to aberrant immune response.
  • Granulomatous lesions produced by specific infections, eg whipworm, mycoses, but differentiated from true granulomatous enteritis.

Pathophysiology

  • Mucosal granulomatous inflammation causing localized marked thickening of intestinal wall → intestinal stenosis may occur, but not always.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Lewis D C (1995) Successful treatment of regional enteritis in a dog. JAAHA 31 (2), 170-173 PubMed.
  • Bright R M, Jenkins C, DeNovo R, McCrackin M A & Toal R (1994) Chronic diarrhea in a dog with regional granulomatous enteritis. JSAP 35 (8), 423-426 VetMedResource.


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