Canis ISSN: 2398-2942

Diarrhea: chronic

Contributor(s): James Simpson, Ken Harkin

Introduction

Pathogenesis

Etiology

  • See specific conditions.

Pathophysiology

  • Impaired digestion/impaired absorption Malabsorption → presence of intraluminal complex molecules → osmotic diarrhea.
  • Some bacterial toxins, and also metabolites of intraluminal bacterial digestion of nutrients, stimulate secretion of fluid from intestine → secretory diarrhea.
  • Intestinal mucosal inflammation → increased mucosal permeability → diarrhea.
  • Altered intestinal motility.

Timecourse

  • Persisting >2 weeks.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Ludlow C L (1995) Methods of testing small intestinal function. Vet Med 90 (10), 934-948 VetMedResource.
  • Simpson J W (1992) Role of nutrition in aetiology and treatment of diarrhea. JSAP 33 (4), 167-171 VetMedResource.
  • Batt R M & Hall E J (1989) Chronic enteropathies in the dog. JSAP 30 (1), 3-12 VetMedResource.
  • Moon H W (1978) Mechanisms in the pathogenesis of diarrhea - a review. JAVMA 172 (4), 443-448 PubMed.

Other sources of information

  • Simpson K W (1996) Small Intestinal Disease. In: BSAVA Manual of Canine and Feline GastroenterologyJ W Simpson, E Hall & D Thomas (editors), BSAVA, Cheltenham. p114.


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