Bovis ISSN 2398-2993

Skin biopsy

Synonym(s): Dermatology

Contributor(s): Vetstream Ltd , Catherine Fraser

Introduction

Introduction

  • Skin histopathology is a valuable aid to differential and definitive diagnosis of many skin disorders.
  • Biopsies can be used for culture and sensitivity of deeper lesions.

Uses

Uses

  • Definitive diagnosis of certain skin diseases.
  • Categorization of skin disease.
  • Exclusion of some diseases.

Punch biopsy 

  • For small samples of generalized or widespread lesions, such as:
  1. Demodicosis.
  2. Sarcoptic mange. Mites: overview
  3. Dermatophilosis.
  4. Dermatophytosis. Ringworm
  5. Onchocerciasis.
  6. Staphylococcal disease. Staph spp
  7. Immune-mediated skin conditions.
  8. Evaluation of urticaria/angioedema Urticaria and angioedema.
  9. Photosensitivity Photosensitization.

Excisional biopsy

Advantages
  • Simple technique.
  • In many cases will confirm or indicate a clear cut diagnosis.
Disadvantages
  • May not yield definitive diagnosis.
  • Chronic inflammatory changes and self-excoriation mask pathologic changes.
  • Sutures, dehiscence.
  • Head and foot lesions may require sedation Sedating cattle.
  • Must be obtained early in course of disease before chronic inflammatory changes occur.
  • Local anesthesia Local anesthesia - overview.

Requirements

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Preparation

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Procedure

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Aftercare

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Outcomes

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Littlewood J D (1997) Diagnostic procedures in equine skin disease. Equine Vet Educ 9,174-176.
  • Hahn R A (1984) Skin biopsy in horses. Mod Vet Pract 65 (2), 122 .

Other sources of information

  • Moriello K A & Mason I S (eds) (1995) Handbook of Small Animal Dermatology. 1st edn. Pergamon. pp 31-33.
  • Muller G H et al (1995) Muller and Kirk's Small Animal Dermatology. 5th edn. Philadelphia: W B Saunders. pp 111-118.


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