Bovis ISSN 2398-2993

Progesterone

Contributor(s): Louise Cox-O’Shea, Vetstream Ltd , Andrea Tarr

Introduction

Name

  • Progesterone.

Class of drug

  • Progestogen.

Description

Chemical name

  • Pregn-4-ene-3,20-dione.

Molecular formula

  • C21H30O2.

Physical properties

  • Intravaginal progesterone releasing device.
  • Single use only.

Storage requirements

  • <30°C.

Uses

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Indications

  • Production enhancement and increases feed efficiency in cattle.
  • Administration of progesterone (or any progestogen) for 10-14 days will suppress Estrus Estrus.
    Administration for longer periods may caused decreased fertility.
  • On removal of the progesterone/progestogen source, the negative feedback on the pituitary and hypothalamus is removed and estrus is initiated. This facilitates the use of artificial insemination and serving by the bull.
  • Synchronisation of groups. Control of estrus in the dairy herd Estrus control in the beef herd.
  • Synchronization of recipient and donor for Embryo transfer Embryo transfer.
  • To be used in combination with prostaglandin.
  • Ensure animal has cycling ovarian activity before treatment.

Administration

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Precautions

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Withdrawal Period

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Adverse Reactions

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Further Reading

Publications

Refereed Papers

Other sources of information

  • Bishop Y (2005) Ed The Veterinary Formulary. 6th edn. Pharmaceutical Press. ISBN: 0-85369-579-2.
  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.
  • Veterinary Medicines Directorate (VMD) Product Information Database. Website: www.vmd.defra.gov.uk.

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