Bovis ISSN 2398-2993

Oxytetracycline

Synonym(s): Tetracycline antibacterial

Contributor(s): Louise Cox-O’Shea, Vetstream Ltd , Andrea Tarr

Introduction

Name

  • Oxytetracycline.

Class of drug

  • Tetracycline antibacterial.

Description

Chemical name

  • [4S-(4-alpha,4a-alpha,5-alpha,5a-alpha,6-beta,12a-alpha)]-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide.

Molecular formula

  • C22H24N2O9.

Physical properties

  • Aqueous solution.
  • Tablets.

Storage requirements

  • <25°C.
  • Protect from light.

Uses

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Indications

Administration

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Pharmocokinetics

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Precautions

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Interactions

With other drugs

  • Antacids and kaolin mixtures reduce oral bioavailability of oxytetracycline.
  • Enhanced anticoagulant effect of warfarin.
  • Reduced activity of concurrently administered bactericidal antimicrobials such as the beta-lactams.

Withdrawal Period

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Adverse Reactions

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Further Reading

Publications

Refereed Papers

Other sources of information

  • Bishop Y (2005) Ed The Veterinary Formulary. 6th edn. Pharmaceutical Press. ISBN: 0-85369-579-2.

Organisation(s)


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