Bovis ISSN 2398-2993

Isometamidium chloride

Contributor(s): Louise Cox-O’Shea , Andrea Tarr

Introduction

Name

  • Isometamidium chloride.

Class of drug

  • Antiprotozoal agent: Trypanocidal.

Description

Chemical name

  • 3-[2-(3-amino-5-ethyl-6-phenylphenanthridin-5-ium-8-yl)iminohydrazinyl]benzenecarboximidamide;chloride

Molecular formula

  • C28H26CIN7

Molecular weight

  • 496.015

Physical properties

  • Powder.
  • Reconstitute for injection with sterile water for injection.

Storage requirements

  • Store in a cool dry place.
  • Protect from light.

Uses

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Indications

  • Trypanocidal.
  • Treatment and prevention of Trypanosomiasis Trypanosomiasis.
  • Active against Trypanosoma congolense, T. vivax,T. brucei and T. evansi.

Administration

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Pharmocokinetics

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Precautions

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Withdrawal Period

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Adverse Reactions

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Further Reading

Publications

Refereed Papers

Other sources of information

  • Pub Chem. Open Chemistry Database. Modified 2017. Isometamidium chloride. U.S. National Library of Medicine, National Center for Biotechnology Information.
  • Trypashish specific product information sheet. Bimeda.
  • Veridium 1g specific product information sheet. Ceva.

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