ISSN 2398-2993      

Imidocarb

obovis
Contributor(s):

Eilidh Thomson

Andrea Tarr


Introduction

Name

  • Imidocarb dipropionate (substituted carbanilide).

Class of drug

  • Anti-protozoal.

Description

Chemical name

  • 1,3'-bis[3-(4,5-dihydro-1 H-imidazol-2-yl)phenyl]urea; propionic acid.

Molecular formula

  • C25H32N6O5.

Molecular weight

  • 496.6 g/mol.

Physical properties

  • Clear amber aqueous liquid.

Storage requirements

  • Do not store above 25oC/77oF.
  • Do not allow to freeze.
  • Protect from light.

Uses

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Indications

  • For treatment and prevention of redwater fever (babesia divergens ) in cattle ONLY.
  • For treatment of anaplasmosis Tick-borne fever (not an authorized indication of the brand Imizol in the UK).
Some Governments (including the UK Government) require notification of treatment with Imidocarb products. For example, in the UK, prescribing and/or treating Veterinarians should notify their Divisional Veterinary Manager/Regional Veterinary Lead "with the name and address of the farmer on whose farm the product is to be administered. They should also inform the farmer that they must notify the DVM/RVL when treated animals are either to be slaughtered or their milk is to be used for human consumption".

Administration

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Precautions

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Withdrawal Period

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Adverse Reactions

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Belloli C, Lai O R, Orma P, Zizzadoro C, Sasso G & Crescenzo G (2006) Pharmacokinetics and mammary elimination of Imidocarb in sheep and goats. J Dairy Sci 89 (7), 2465-2472 PubMed.
  • Adams L G, Corrier D E & Williams J D (1980) A study of the toxicity of Imidocarb diproprionate in cattle. Res Vet Sci 28 (2), 172-177 PubMed.

Other sources of information

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