Bovis ISSN 2398-2993

Eprinomectin

Synonym(s): Avermectin, macrocyclic lactone, parasiticide

Contributor(s): Louise Cox-O’Shea, Vetstream Ltd , Andrea Tarr

Introduction

Name

  • Eprinomectin.

Class of drug

  • Avermectin.
  • Macrocyclic lactone

Description

Chemical name

  • (1'R,2S,4'S,5S,6R,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-21',24'-Dihydroxy-6-isopropyl-5,11',13',22'-tetramethyl-2'-oxo-5,6-dihydrospiro[pyran-2,6'-[3,7,19]trioxatetracyclo[15.6.1.14,8.020,24 ]pentacosa[10,14,16,22]tetraen]-12'-yl 4-O-(4-acetamido-2,4,6-trideoxy-3-O-methyl-α-L-lyxo-hexopyranosyl)-2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside - (1'R,2S,4'S,5S,6R,8'R,10'E,12'S,1 3'S,14'E,16'E,20'R,21'R,24'S)-6-[(2S)-2-buta.                  

Molecular formula

  • C99H148N2O28.

Molecular weight

  • 1814.231 Da.

Physical properties

  • Pour on solution.

Uses

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Indications

Administration

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Pharmocokinetics

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Precautions

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Withdrawal Period

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Adverse Reactions

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Further Reading

Publications

Refereed Papers

Other sources of information

  • Chemspider (2015) Eprinomectin. [online] Available at: www.chemspider.com.
  • Bishop Y (2005) Ed The Veterinary Formulary. 6th edn. Pharmaceutical Press. ISBN: 0-85369-579-2. pp 188 & 209.
  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

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