Bovis ISSN 2398-2993

Clenbuterol hydrochloride

Synonym(s): Uterine muscle relaxant

Contributor(s): Louise Cox-O’Shea , Andrea Tarr

Introduction

Name

  • Clenbuterol hydrochloride.

Class of drug

  •  Uterine muscle relaxant.

Description

Chemical name

  • 1-(4-Amino-3,5-dichlorophenyl)-2-tert-butylaminoethanol.

Molecular formula

  • C12H18Cl2N2O.

Molecular weight

  • 277.19.

Storage requirements

  • Store at temperatures below 25°C.
  • Protect from light.
  • Use or discard within 28 days of withdrawing first dose.

Uses

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Indications

  •  Delay parturition in heifers (allowing preparation of soft birth canal).
  •  To facilitate manipulation in cases of dystocia. Dystocia
  •  Cesarean-section: relax uterine muscle Cesarean.
  •  Delay parturition eg to allow calving to be monitored - for instance avoid night time calving.
  •  Prolapsed uterus - facilitate replacement. Uterine prolapse
  •  Embryo transfer - reduce trauma to uterus during manipulation. Embryo transfer

Administration

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Pharmocokinetics

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Precautions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Interactions

With other drugs

  •  Do not use concurrently with:
    • Atropine, adrenoceptor stimulants, vasodilators, general anesthetics.
      • As possible hypotensive effects.
  • Do not use with:
    • Oxytocin, prostaglandins.
      • As is antagonistic.
    • Other Beta-sympathomimetics/ vasodilators.
      • due to possible additive effects.

Withdrawal Period

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to purchase a 30 day trial, or Login

Further Reading

Publications

Refereed Papers

Other sources of information

  • NOAH compendium of datasheets.

ADDED