ISSN 2398-2993      

Chlorphenamine

obovis

Synonym(s): chlorpheniramine, antihistamine


Introduction

Name

  • Chlorphenamine.

Class of drug

  • H1 antihistamine.

Description

Chemical name

  • Gamma-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine.
  • 2-[p-chloro-alpha-(2-dimethylaminoethyl)benzyl]pyridine.

Molecular formula

  • C16H19ClN2.

Molecular weight

  • 274.788.

Physical properties

  • Odorless, white, crystalline powder. Soluble in water and alcohol.
  • 1 g soluble in 4 ml water.
  • Oily liquid.
  • Tablets.

Storage requirements

  • Store in tight and well-closed containers, at room temperature.
  • Injectable preparations should be stored in light-resistant containers.

Uses

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Indications

  • Allergies.
  • Anaphylactic reactions. Anaphylaxis and urticaria
  • Commonly used in companion animals as premedication before transfusions and certain chemotherapeutic agents.
  • May reduce pruritus in some conditions.  Photosensitization
  • In cattle; may be used in conjunction with antimicrobials (& less commonly corticosteroids) in the treatment of respiratory diseases.
  • Weak sedative.

Administration

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Pharmacokinetics

Precautions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Interactions

With other drugs

  • CNS depressant drugs.

Withdrawal Period

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Adverse Reactions

This article is available in full to registered subscribers

Sign up now to obtain ten tokens to view any ten Vetlexicon articles, images, sounds or videos, or Login

Further Reading

Publications

Refereed Papers

Other sources of information

  • Yolande Bishop (ed) (2005) The Veterinary Formulary. 6th edn. Published in association with the British Veterinary Association.
  • The European agency for the evaluation of medicinal products (1999) Committee for medicinal products; chlorphenamine. Summary report.
  • Neocell pharmaceuticals [online]. Veterinary medicines for large animals -ancesol 10mg/ml. Website: www.neocell.gr. Last accessed 15th March 2018.
  • Richter pharma ag [online]. Overview Richter pharma products: ancesol. Website: www.ritcher-pharma.ag. Last accessed 15th March 2018.
  • Veterinary medicines directorate [online]. VMD product database. Website: www.vmd.defra.gov.uk. Last accessed 15th March 2018.
MEMBER BENEFIT

Can’t find what you’re looking for?

We have an ever growing content library on Vetlexicon so if you ever find we haven't covered something that you need please fill in the form below and let us know!

 
 
 
 

To show you are not a Bot please can you enter the number showing adjacent to this field

 Security code