Bovis ISSN 2398-2993

Acepromazine

Synonym(s): Acetylpromazine

Contributor(s): Louise Cox-O’Shea, Vetstream Ltd , Andrea Tarr

Introduction

Name

  • Acepromazine.

Class of drug

  • Phenothiazine sedative.

Description

Chemical name

  • 1-[10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-yl]ethanone.
  • 10-[3-(dimethylamino)propyl]phenothiazin-2-yl methyl ketone.

Molecular formula

  • C19H22N2OS.C4H4O4.

Physical properties

  • Pale yellow injectable solution, gel or tablets.
Licensing laws vary between countries for ACP. Always check specific product information and ensure that you adhere to local rules
Acepromazine is not licensed for use in cattle in the UK.

Storage requirements

  • <25°C.
  • Protect from light.

Uses

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Indications

  • Pre-anesthetic medication.
  • Sedation.
  • Tranquilization.

Administration

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Pharmocokinetics

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Precautions

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Interactions

With other drugs

  • Other central nervous system (CNS) depressant agents, may cause additive CNS depression if used with acepromazine.

Withdrawal Period

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Adverse Reactions

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Further Reading

Publications

Refereed Papers

Other sources of information

  • Haskell S, Gehring R, Payne M, Craigmill A, Webb A,  Baynes R & Riviere (2017) Digest, Update on FARAD food animal drug withholding recommendations. [online]. Available at: www.farad.org. 
  • Steneroden K & Wydallis E (2014) Veterinary Drug Formulary.
  • Yolande Bishop (2005) The Veterinary Formulary. 6th edn. Published in association with the British Veterinary Association.
  • NOAH compendium of datasheets.
  • VMD product database.

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