Bovis ISSN 2398-2993

Anesthesia: drug interactions

Synonym(s): Pharmacodynamics, pharmacokinetics
 

Contributor(s): Vetstream Ltd , Gayle Hallowell

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Introduction

  • Multiple drug therapy is common in veterinary practice, but due to cattle being food-producing animals we are often limited in the drugs that we can administer.
  • Drug interaction may result in a loss of activity, an increase in activity or an increase in the side-effects or toxicity of a drug.
  • Drug interactions can be physical, pharmacodynamic or pharmacokinetic.

Pharmacodynamic interactions

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Pharmacokinetic interactions

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Specific drug interactions

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMed Resource.
  • Seddighi R & Doherty T J (2016) Field Sedation and Anesthesia of Ruminants. Vet Clin North Am Food Anim Pract 32 (3), pp 553-570 PubMed
  • Abrahamsen E J (2013) Chemical restraint and injectable anesthesia of ruminants. Vet Clin North Am Food Anim Pract 29 (1), pp 209-27 PubMed
  • Smith G (2013) Extralabel use of anesthetic and analgesic compounds in cattle. Vet Clin North Am Food Anim Pract 29 (1), pp 29-45 PubMed.

Other sources of information

  • Valverde A & Sinclair M (2015) Ruminant Anesthesia. In: Veterinary Anesthesia and Analgesia. 5th Edn. Wiley-Blackwell.
  • Clarke K & Trim C (2014) Patient Monitoring and Clinical Measurement and Anaesthesia of Cattle. In: Veterinary Anaesthesia. 11th Edn. Elsevier.
  • Bishop Y (2000) The Veterinary Formulary. 4th edn. Pharmaceutical Press.


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