Tonsil: squamous cell carcinoma


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  • Oral neoplasms comprise 10% of feline neoplasms.
  • 60-70% of feline oral tumors are squamous cell carcinomas.
  • 10% of feline oral squamous cell carcinomas arise in the tonsil.
  • Typically unilateral.
  • More aggressive biological behavior than other oral squamous cell carcinomas.
  • Signs: Hypersalivation, difficulty in swallowing or eating.
  • Diagnosis: signs, biopsy.
  • Prognosis: poor - an aggressive neoplasm with much higher rate of regional lymph node and distant metastasis than other oral squamous cell carcinomas


Clinical signs

  • Hypersalivation.
  • Frequent regional lymph node enlargement.


Differential diagnosis

  • Traumatic or other stomatitis    .
  • Other tonsillar neoplasms (e.g. lymphosarcoma).
  • Tonsillar cyst (rare).
  • Other causes of hypersalivation (toxicosis, periodontal disease, calicivirus, chronic stomatitis, gingivitis etc.)



  • Poor prognosis due to early metastasis.

Reasons for treatment failure

  • Rapid progression of tumor.
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