- Cause : idiopathic but speculatively it may be associated with tapeworm infestation or virus infection.
- Signs : a syndrome of prolapse of the third eyelids (nictitating membranes) often with diarrhea as well.
- Occasionally cats can be ill but they will recover with supportive care.
- Diagnosis : usually just on signs.
- Treatment : none.
- Prognosis : good, generally completely benign and self-limiting.
- Bilateral third eyelid protrusion.
- No ocular abnormalities.
- Intestine containing excess gas and fluid.
- No detectable anomalies.
- Rarely there is evidence of weight loss or a pyrexia.
- Other causes of bilateral third eyelid protrusion:
- Other causes of diarrhea including:
- Viral enteritis: parvovirus [Feline panleucopenia virus disease] , enteric coronaviruses [Feline corona virus: FIP] .
- Bacterial enteritis: Salmonella spp, Campylobacter spp.
- Enteric parasites: Isospora spp , Giardia , roundworms, possibly tapeworms.
- Food intolerance.
- Food allergy .
- Inflammatory bowel disease .
- Systemic disease: kidney failure , liver disease , hyperthyroidism .
- Systemic viral infection: Feline Immunodeficiency Virus , Feline Leukemia Virus .
- Small intestinal bacterial overgrowth.
- Intestinal neoplasia especially lymphoma .
- Exocrine pancreatic insufficiency .
- All cats seem to recover but the time course varies considerably.
It is unusual for the recovery to take <4 or >16 weeks.
Expected response to treatment
- Retraction of third eyelids to normal position.
- Resolution of diarrhea.
Reasons for treatment failure
- Incorrect diagnosis → other cause of diarrhea untreated.